Ski2-like DExH

Group Yeast name Human name TRanscription pre-mRNA splicing RNA export Translation RNA decay Ribosome Biogenesis Mitochondrial RNA processing other functions
Ski2 Ski2p SkiV2              
Mtr4p SkiL2
Brr2 Brr2p U5-200kD
Slh1p HelC
Hfm1p Hfm1
Suv3p* Suv3*
  • (a)  Mtr4p is involved in other RNA processing events, including tRNA maturation etc.
  • (b)  DNA helicase, catalyzes the unwinding of Holliday junctions; has ssDNA and dsDNA stimulated ATPase activity
     involved in the conversion of double-stranded breaks to later recombination intermediates and in crossover control
  • (d)  DNA: recombination and repair
  • * Suv3 does not directly group with the Ski2 like DExH proteins, it rather represents its own branch.
  • There is one uncharacterized Ski2-like DExH protein in E.coli: Q6XGE6  Swissprot >